Early diagnosis of cancer of the ovary, in fact, has a characteristic: it is tremendously “Bravo” to hide, especially in the initial phases. The few signs in some way related to its onset, such as swelling and pain undefined the belly, as well as the difficulties to go to the bathroom, are red flags that are often underestimated or confused. Instead should be arguments referred to speak immediately with the gynecologist who can then, in addition to the visit, proceed to a transvaginal ultrasound and abdominal, which can start then all necessary investigations to reveal the nature of the framework that you are composing. The Council is valid for all, but it becomes even more important for those who have just crossed the threshold of menopause. According to the statistics, in fact, cases of the disease are identified mainly in the decade between 50 and 60 years.
There are, it is true, other elements that can in some way represent a possible increased risk for the development of this neoplasia, seventh in the female population. For example, you must do more attention when menstruation began very early and menopause arrived late. On the security front, it appears that the use of oral contraceptive can represent a positive element, so as to have had more children and have breastfed. The important thing, in any case, is arriving soon: when the tumor is still limited to the organ and the diseased cells are not yet widespread, the prospects for complete healing is profoundly modified.
Care, increase the hopes
Once you have identified ovarian cancer, depending on its characteristics and to the possible spread, the first step is the surgical intervention to eliminate in addition to a component also other possible areas of “nicked” from the disease. The specialist can then suggest a treatment of chemotherapy, which appears to be of crucial importance especially if the tumor that is removed is at an advanced stage. The goal, in this case, is obviously “clean” completely the organism from the pathological cells, also doing so to remove the supplies to the tumor.
For this, although there are many schemes of care that are to be identified on a case by case basis, together with the classical chemotherapy is often recommended a treatment anti-angiogenesis, which aims to reduce the formation of new blood vessels necessary to the tumor to grow. In recent times, then, is proving a great help new therapies, and in particular the drugs PARP inhibitors, who must always be indicated on the basis of the characteristics of the tumor cells. These medicines act on the mechanisms of DNA repair and, according to what emerged at the recent congress of the European Association for Medical Oncology (ESMO) held in Barcelona, may prove highly effective.
Genetics, a risk factor
Some time ago has done much to discuss the choice of Angelina Jolie. The presence of the gene mutation BRCA1 would raise 87% the risk of malignant tumors of the breast and 50 percent to ovarian cancer, for which the plaintiff has proceeded to eliminate at the origin the risks. In the case of positivity to genetic testing, especially if there is also a positive response to another gene (BRCA2) the probability of getting sick of breast cancer is growing exponentially. The actress has brought to the fore a problem ever more significant, for the attention that it leads to genetic testing. The National Cancer Institute reveals that nearly 10 percent of cancers of the ovary could be tied to a genetic alteration that transmits through inheritance. Under the magnifying glass of science there are two genes, with their respective mutation: are called BRCA1 and BRCA2. Are important as regards both ovarian cancers that the breast and in the presence of this mutation you can think of a possible “anticipation” of the disease compared to the age.
In families with many cases of ovarian cancer or breast carcinoma (more precisely, more cases of the same type of tumor or two cancers associated to the same genetic alteration, as those of ovarian and breast, in the same branch of the family) it is useful to contact a specialized center in genetic counselling at a Cancer Institute of national importance. If a person was the bearer of one of these genetic mutations, it is advisable to follow a program of close surveillance with mammography and ultrasound”. Without forgetting that there is still a risk factor, which does not presuppose the systematic appearance of neoplasia. But increases the risk: then it is important that you follow correct lifestyles in preventive key.